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Semaglutide

What is Semaglutide?

Semaglutide, often referred to by the brand name Ozempic, is a GLP-1 (glucagon-like peptide 1) analog prescribed for managing weight loss. It activates the GLP-1 receptor after binding to it. It stimulates insulin secretion and helps minimize the blood glucose level.

GLP-1 is a hormone that controls blood glucose levels through different mechanisms, including:

  • Insulin secretion
  • Slowing the process of gastric emptying
  • Minimizing postprandial glucagon secretion
Semaglutide shares a lot of similarities with the natural GLP-1 hormone. Hence, it acts as an analog of this hormone and promotes insulin production by stimulating the islet cells in the pancreas. Semaglutide proves to be useful as a weight loss treatment. Especially in hypercholesterolemia, this lowers the progression of atherosclerosis by decreasing inflammation and gut permeability. Thus, the reduction in appetite tends to cause weight loss.

What Forms of Semaglutide are Available?

Semaglutide is available in the form of subcutaneous injections and tablets.

What is the Point of Taking Semaglutide?

Clinical trials suggest that Semaglutide helps reduce glycosylated hemoglobin (HbA1c) levels and, thus, lower body weight. Subcutaneous injection administration is prescribed once a week, while one tablet is prescribed daily. With limited doses administered, Semaglutide has a competitive advantage over other types of weight loss options.  

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Why would I Want to Use Semaglutide?

  • Recently, FDA has approved Semaglutide for weight management (chronic) in adults
  • Recently, FDA has approved Semaglutide for weight management (chronic) in adults
  • The EMA and Health Canada have approved the use of Semaglutide as a weight management drug.

Health Benefits of Semaglutide Over Time

  • After 12 weeks of administration, Semaglutide can help minimize the HbA1c level, systolic blood pressure, as well as body weight.
  • Semaglutide also reduces VLDL cholesterol and fasting triglycerides, which also improves cardiovascular health.

What You Need to Know?

Semaglutide administration could cause some side effects, including nausea, vomiting, diarrhea, abdominal pain, constipation, etc.
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